Latest research on cord clamping

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We will continously blog on our own and others results on cord clamping, as well as other news related to the subject, such as umbilical cord milking and resuscitation.

Latest posts from the blog

11 February 2017
In memory of Hans Rosling:

Curiosity. Commitment. Factfullness.
On three occasions, Hans tweeted about our research. Obviously, I was both surprised and proud that this occupied and certainly hard courted person had time to follow what we've done. Now he is deceased, lost to all of us, but especially of course for his family, friends and loved ones.
There are many who have shared their memory of Hans Rosling during the recent days, yet I cannot help but share my thoughts with you.
We are many who admire Hans and what he accomplished, from his many years of work as a doctor in Africa, his research and start-up of programs in global health and his work with Gapminder. His humanism. In all I think three words shines brightly:
Curiosity. Commitment. Factfullness.
Hans always seemed to be curious, to phenomena in the world around us, curious on people, to figure out how the earth can be better place to live. The altruistic commitment he radiated, the commitment to spread knowledge, to help people, the passion to reach out, not to gain personal benefit, but for everyone's best. And then the word that Hans is said to have coined, and he was writing a book about: factfulness. To see past our own beliefs and prejudices. The ability to see the reality that is in front of us and to base our arguments on facts and not something else.
This last has never been so important as today, when many of us so easily begin to listen to the populists and the prophets of doom, the Trumps and right extremes.
Others have written that Hans Rosling's voice was more important now than ever before. I guess what we really should say is that everyone's vote is more important than in a long time.
When similar winds as from before World War II blows cold all around us, then it is time to join Hans Rosling disciples to become apostles: Start with a good dose of humanism and add thereto Curiosity. Commitment. And perhaps above all Factfulness.
Thanks for all Hans. I will try my best to honor your memory.

Memorial fund in honor of Hans Rosling
​​​​​​​https://unicef.se/egna-insamlingar/3866-memorial-fund-in-honor-of-hans-rosling​​​​​​​

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22 January 2017
3 reasons for clamping the umbilical cord after 3 minutes
14 January 2017
30 seconds might be enough when delaying cord clamping at cesarean sections

Research

Latest posts on NEW research

Two of the persons involved in the development of Lifestart trolley (http://www.inditherm.com/medical/neonatal-resuscitation-lifestart/) has published a review in Maternal Health, Neonatology and Perinatology.
"Abstract: The rationale for keeping the mother and her newborn together even when neonatal resuscitation is required is presented. The development of a customised mobile resuscitation trolley is detailed explaining how the resuscitation team can be provided with all the facilities of a standard resuscitation trolley to resuscitate the neonate at the mother’s side with an intact cord. Alternative low tech solutions which may be appropriate in low resource setting and with a low risk population are also described."

http://mhnpjournal.biomedcentral.com/articles/10.1186/s40748-016-0034-9

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9 July 2015
Delayed clamping vs. milking in preterm infants
12 June 2015
Review on delivery room management of newly born infants
23 May 2015
Cardiac changes during delayed cord clamping
3 May 2015
Delayed cord clamping with and without cord stripping: a prospective randomized trial of preterm neo
12 April 2015
Delayed cord clamping in South African neonates with expected low birthweight

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  • Effectiveness of Stabilization of Preterm Infants With Intact Umbilical Cord Using a Purpose-Built Resuscitation Table-Study Protocol for a Randomized Controlled Trial.


    Related Articles
    Effectiveness of Stabilization of Preterm Infants With Intact Umbilical Cord Using a Purpose-Built Resuscitation Table-Study Protocol for a Randomized Controlled Trial.
    Front Pediatr. 2019;7:134
    Authors: Knol R, Brouwer E, Klumper FJCM, van den Akker T, DeKoninck P, Hutten GJ, Lopriore E, van Kaam AH, Polglase GR, Reiss IKM, Hooper SB, Te Pas AB
    Abstract
    Background: Most preterm infants fail to aerate their immature lungs at birth and need respiratory support for cardiopulmonary stabilization. Cord clamping before lung aeration compromises cardiovascular function. Delaying cord clamping until the lung has aerated may be beneficial for preterm infants by optimizing hemodynamic transition and placental transfusion. A new purpose-built resuscitation table (the Concord) has been designed making it possible to keep the cord intact after preterm birth until the lung is aerated and the infant is respiratory stable and breathing [Physiological-Based Cord Clamping (PBCC)]. The aim of this study is to test the hypothesis whether stabilizing preterm infants by PBCC is at least as effective as the standard approach using time-based Delayed Cord Clamping (DCC). Study design: This is a randomized controlled non-inferiority study including 64 preterm infants born at <32 weeks of gestation. Infants will be randomized to either the PBCC approach or standard DCC. In case of PBCC, infants will be stabilized with an intact umbilical cord and the cord will only be clamped when the infant is considered respiratory stable, defined as the establishment of regular spontaneous breathing, a heart rate ≥100 bpm and oxygen saturation above 90% while using inspired fraction of oxygen (FiO2) < 0.40. The Concord will be used, which allows giving respiratory support with an intact umbilical cord. In the DCC group infants are clamped first before they are transferred to the standard resuscitation table for further treatment and stabilization. Cord clamping is time-based and delayed at 30-60 s. The primary outcome will be the time to respiratory stability of the infant, starting from birth. Secondary outcomes will include details of stabilization, important clinical outcomes of prematurity and maternal safety outcomes. Discussion: We expect that PBCC using the Concord may reduce major morbidities and mortality in preterm infants. The current study protocol will assess the effectivity of stabilization. Once effectivity of stabilization is confirmed, we will start a large multicenter randomized clinical trial to investigate whether PBCC reduces mortality and morbidity in preterm infants compared to the standard approach. Trial registration: Netherlands Trial Registry NTR7194, registered on April 20th, 2018.
    PMID: 31106181 [PubMed]

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