Latest research on cord clamping

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We will continously blog on our own and others results on cord clamping, as well as other news related to the subject, such as umbilical cord milking and resuscitation.

Latest posts from the blog

11 February 2017
In memory of Hans Rosling:

Curiosity. Commitment. Factfullness.
On three occasions, Hans tweeted about our research. Obviously, I was both surprised and proud that this occupied and certainly hard courted person had time to follow what we've done. Now he is deceased, lost to all of us, but especially of course for his family, friends and loved ones.
There are many who have shared their memory of Hans Rosling during the recent days, yet I cannot help but share my thoughts with you.
We are many who admire Hans and what he accomplished, from his many years of work as a doctor in Africa, his research and start-up of programs in global health and his work with Gapminder. His humanism. In all I think three words shines brightly:
Curiosity. Commitment. Factfullness.
Hans always seemed to be curious, to phenomena in the world around us, curious on people, to figure out how the earth can be better place to live. The altruistic commitment he radiated, the commitment to spread knowledge, to help people, the passion to reach out, not to gain personal benefit, but for everyone's best. And then the word that Hans is said to have coined, and he was writing a book about: factfulness. To see past our own beliefs and prejudices. The ability to see the reality that is in front of us and to base our arguments on facts and not something else.
This last has never been so important as today, when many of us so easily begin to listen to the populists and the prophets of doom, the Trumps and right extremes.
Others have written that Hans Rosling's voice was more important now than ever before. I guess what we really should say is that everyone's vote is more important than in a long time.
When similar winds as from before World War II blows cold all around us, then it is time to join Hans Rosling disciples to become apostles: Start with a good dose of humanism and add thereto Curiosity. Commitment. And perhaps above all Factfulness.
Thanks for all Hans. I will try my best to honor your memory.

Memorial fund in honor of Hans Rosling

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22 January 2017
3 reasons for clamping the umbilical cord after 3 minutes
14 January 2017
30 seconds might be enough when delaying cord clamping at cesarean sections


Latest posts on NEW research

Two of the persons involved in the development of Lifestart trolley ( has published a review in Maternal Health, Neonatology and Perinatology.
"Abstract: The rationale for keeping the mother and her newborn together even when neonatal resuscitation is required is presented. The development of a customised mobile resuscitation trolley is detailed explaining how the resuscitation team can be provided with all the facilities of a standard resuscitation trolley to resuscitate the neonate at the mother’s side with an intact cord. Alternative low tech solutions which may be appropriate in low resource setting and with a low risk population are also described."

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9 July 2015
Delayed clamping vs. milking in preterm infants
12 June 2015
Review on delivery room management of newly born infants
23 May 2015
Cardiac changes during delayed cord clamping
3 May 2015
Delayed cord clamping with and without cord stripping: a prospective randomized trial of preterm neo
12 April 2015
Delayed cord clamping in South African neonates with expected low birthweight


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Google Alert - cord clamping

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  • Effect and safety of timing of cord clamping on neonatal hematocrit values and clinical outcomes in term infants: A randomized controlled trial.

    Related Articles
    Effect and safety of timing of cord clamping on neonatal hematocrit values and clinical outcomes in term infants: A randomized controlled trial.
    J Perinatol. 2018 03;38(3):251-257
    Authors: Chen X, Li X, Chang Y, Li W, Cui H
    OBJECTIVE: To evaluate the effect and safety of different umbilical cord clamping (UCC) timing.
    STUDY DESIGN: This was a randomized trial of 720 term mothers/infants from the Tianjin Central Hospital of Obstetrics and Gynecology delivered from December 2014 to May 2015 and randomized to immediate cord clamping (ICC) within 15 s, delayed cord clamping (DCC) by 30, 60, 90, 120, 150, or 180 s, or when the umbilical cord pulsation ceased.
    RESULTS: 24 h after delivery, the mean infant hematocrit levels were 56.5, 57.3, 58.8, 59.7, 59.5, 59.7, 60.3, and 61.0% in the ICC, 30, 60, 90, 120, 150, and 180-second DCC, and no pulsation groups, respectively (P = 0.021, 0.001, 0.003, 0.001, <0.001, and <0.001, respectively; standard deviations ranging 5.4-8.7%). There was no significant difference between the 30-second DCC and ICC groups. No significant differences were found in other neonatal and maternal outcomes among these groups.
    CONCLUSION: For term infants, DCC increases the hematocrit values, without apparent harmful effects on the infants and their mothers.
    PMID: 29255190 [PubMed - indexed for MEDLINE]
  • Whole blood volumes associated with milking intact and cut umbilical cords in term newborns.

    Related Articles
    Whole blood volumes associated with milking intact and cut umbilical cords in term newborns.
    J Perinatol. 2018 03;38(3):245-250
    Authors: McAdams RM, Fay E, Delaney S
    OBJECTIVE: The objective of this study is to determine placental transfusion blood volumes with intact and cut umbilical cord milking in term newborns.
    STUDY DESIGN: Sixty women at ≥37 weeks' gestation were enrolled. Following delivery, the umbilical cord was immediately clamped and cut to separate the newborn. Either intact umbilical cord milking (I-UCM) of the placental-umbilical cord unit or cut umbilical cord milking (C-UCM) of the cut umbilical cord segment was performed. For I-UCM, the cord underwent milking three or four times while being attached to placental circulation. For C-UCM, a 10, 20, or 30 cm cord segment was cut separately and milked four times. Blood volumes were compared between I-UCM and C-UCM methods.
    RESULTS: Mean blood volume with I-UCM (×4) was increased compared to the 30 cm C-UCM technique (48.5 ± 19.0 vs. 24.8 ± 4.0 mL, P < 0.001). For C-UCM, blood volume increased proportionally to cord length and, by the second milking, 98.1 ± 4.5% of blood volume was delivered.
    CONCLUSION: I-UCM provides a greater blood volume than C-UCM. With C-UCM, milking the cord more than twice offers no additional advantage.
    PMID: 29234147 [PubMed - indexed for MEDLINE]
  • Umbilical cord milking at birth for term newborns with acidosis: neonatal outcomes.

    Related Articles
    Umbilical cord milking at birth for term newborns with acidosis: neonatal outcomes.
    J Perinatol. 2018 03;38(3):240-244
    Authors: Katheria A, Mercer J, Brown M, Rich W, Baker K, Harbert MJ, Pierce B, Hassen K, Finer N
    OBJECTIVE: To determine if umbilical cord milking is detrimental in compromised term/near-term infants.
    STUDY DESIGN: A retrospective analysis of infants with abnormal cord gases (cord arterial or venous pH of ≤ 7.1 or base deficit > -12). We collected maternal risk factors, cord management, birth, and neonatal outcomes during hospitalization.
    RESULT: We found 157 infants who met the criteria for abnormal cord gases. Thirty-six of those had umbilical cord milking at delivery. There was no significant difference in neonatal outcomes, but fewer infants in the cord milking group needed resuscitation (38 vs. 56%, p = 0.07) and ongoing respiratory support (19 vs. 31%, p = 0.16) compared to the immediate clamping group.
    CONCLUSIONS: While not significant, infants who received cord milking at birth needed less resuscitation and ongoing respiratory support. This study suggests that umbilical cord milking appears to be a safe therapy when acidosis is present and when resuscitation is needed.
    PMID: 29234144 [PubMed - indexed for MEDLINE]

ALtimetric score

Measure of how our paper in JAMA Pediatrics 2017 on anemia is spread by media

Measure of how our paper in JAMA Pediatrics 2015 on neurodevelopment is spread by media